From cast10-request@bevo.che.wisc.edu Tue May 30 06:14:24 2000 Received: (from slist@localhost) by bevo.che.wisc.edu (8.9.1/8.9.1) id GAA25403; Tue, 30 May 2000 06:14:24 -0500 (CDT) Resent-Date: Tue, 30 May 2000 06:14:24 -0500 (CDT) MIME-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Message-ID: <14643.41615.596402.74618@bahaha.che.wisc.edu> Date: Tue, 30 May 2000 06:14:23 -0500 (CDT) From: Age Smilde To: cast10@bevo.che.wisc.edu Subject: CAST: PhD position X-CAST-Category: jobs doctoral 2000-11 Content-Transfer-Encoding: 8bit X-MIME-Autoconverted: from quoted-printable to 8bit by bevo.che.wisc.edu id GAA11032 Resent-Message-ID: <"u0JIpU_bn5M.A.ggG.QK6M5"@bevo.che.wisc.edu> Resent-From: cast10@bevo.che.wisc.edu X-Mailing-List: X-Loop: cast10@bevo.che.wisc.edu Precedence: list Resent-Sender: cast10-request@bevo.che.wisc.edu Sender: cast10-request@bevo.che.wisc.edu Errors-To: cast10-request@bevo.che.wisc.edu ----------------------------------------------------------------- NOTE: Past postings on the CAST10 Email List are archived on the World Wide Web at http://www.che.wisc.edu/cast10 ----------------------------------------------------------------- PhD Student Ship: Spectroscopic in-line batch process monitoring for improving tablet production quality The PhD position described is based on a joint project between Analytical Development at Novo Nordisk, Måløv, Denmark and the Process Analysis and Chemometrics group of the Department of Chemical Engineering at the University of Amsterdam, the Netherlands. Project Description During this PhD project the applicability of spectroscopic analytical technology, e.g. NIR/IR and Raman, will be studied for batch process monitoring. The processes to be studied will be in relation with the production of tablets within the pharmaceutical industry. The combination of chemical and/or physical information regarding the raw materials used and the actual real time batch monitoring will result in data that enable the operators to monitor/maintain and, at the same time, control the quality of the tablet production process. Two of the main areas of research defined in this project are: - Interfacing of the analytical chemistry, spectroscopy, with the tablet manufacturing process - Building mathematical models to find critical relations between the generated spectra and the manufacturing process being monitored. The project will be multi-disciplinary involving e.g., analytical chemistry, formulation chemistry, mathematics/chemometrics and technical engineering. The final goal of the project is to link analytical technology with tablet production. The project is a corporation between the University of Amsterdam, the Netherlands and Novo Nordisk, Måløv, Denmark. Most of the actual training and education, regarding e.g. chemometrics, during the project will take place in Amsterdam while the measuring on processes in relation with tablet production will be in Denmark. The PhD degree resulting from this project is going to be obtained at the University of Amsterdam. Requirements Candidates should preferably have a degree in chemical engineering and/or analytical chemistry or a similar type of education. Affinity with chemometrics and spectroscopy is an advantage. Information More information about the project can be obtained from Dr. D.T. Witte, Novo Nordisk AS, email Erwi@novo.dk or Prof. dr. A.K. Smilde, University of Amsterdam, email asmilde@its.chem.uva.nl. Written applications, including a Curriculum Vitae, should be sent to: Dr. D.T. Witte Analytical Development, Products Novo Nordisk Park 2760 Måløv, Denmark ------------------------------------------- Age K. Smilde Process Analysis and Chemometrics Department of Chemical Engineering University of Amsterdam Nieuwe Achtergracht 166 1018 WV Amsterdam The Netherlands Phone: 31-20-525 5062 Fax: 31-20-525 5604 Email: asmilde@its.chem.uva.nl Web: www-its.chem.uva.nl/research/pac -------------------------------------------